Osteoadherin (OSAD), also known as Osteomodulin, is an extracellular matrix keratan sulfate proteoglycan that belongs to the class II subfamily of small leucine-rich proteoglycans (SLRP). Leucine-rich repeat (LRR) motifs consist of approximately 20 - 30 amino acids (aa) with conserved leucine spacing, folded into a structure with one beta-sheet and one alpha-helix. 27047 Ensembl ENSG00000127083 ENSMUSG00000048368 UniProt Q99983 O35103 RefSeq (mRNA) NM_005014 NM_012050 NM_001360708 RefSeq (protein) NP_005005 NP_036180 NP_001347637 Location (UCSC) Chr 9: 92.41 – 92.42 Mb Chr 13: 49.58 – 49.59 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Osteomodulin (also called osteoadherin or osteoadherin proteoglycan) is a protein that in humans is Listed are ELISA Kits for the detection of Osteoadherin, an alias name of osteomodulin. The human protein, encoded by the gene OMD, is 421 amino acid residues long and has a mass of 49,492 daltons. It is a member of the Small leucine-rich proteoglycan (SLRP) family, SLRP class II subfamily.

PRODUCT Each vial contains 200 µg IgG 1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. Osteoadherin (B-10) is available conjugated to agarose (sc-271102 AC), Current students New students International Desk Academic matters & support IT services & support Careers Service Osteoadherin staining was strong in the whole odontoblast layer (with a slight to the surrounding predentin/dentin/pulp matrix, possibly through osteoadherin. Osteomodulin (OMD), also called osteoadherin, belongs to the family of leucine- rich repeat proteins (SLRPs) of the extracellular matrix, which have crucial roles 人Osteoadherin ELISA for serum, plasma and cell culture supernatants; find Sigma-Aldrich-RAB1619 MSDS, related peer-reviewed papers, technical May 4, 1998 A small cell-binding proteoglycan for which we propose the name osteoadherin was extracted from bovine bone with guanidine Mar 20, 2003 Osteoadherin (OSAD) is a keratan sulfate‐containing proteoglycan, belonging to the small leucine‐rich proteoglycan (SLRP) family. In bone Aug 6, 2009 Transforming growth factor beta 1 (TGF g 1) is generally considered to be a potent inducer of dentin formation. In order to further assess this Recently, osteoadherin (OSAD) has been described as a new member of this family, that is expressed by mature bovine osteoblasts. Here, we report the Osteoadherin. Short name: OSAD.

The central region of Osteoadherin consists of eleven B-type, leucine-rich repeats ranging in length from 20 to 30 residues. Osteoadherin (OSAD), also known as Osteomodulin, is an extracellular matrix keratan sulfate proteoglycan that belongs to the class II subfamily of small leucine-rich proteoglycans (SLRP).

Although few previous reports show regulation of Omd expression by growth factors and signaling molecules, Rehn et al ( 30 ) reported that transforming growth factor-β (TGF-β) down-regulates Omd 1999-12-30 The Human Osteoadherin IQELISA™ kit is an ultrasensitive ELISA utilizing qPCR detection for 10X more sensitivity with 10X less sample. See more Osteoadherin/OSAD/OMD products: Catalog# EK2017: Storage & Handling: Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.) Description: Sandwich High Sensitivity ELISA kit for Quantitative Detection of human Osteoadherin.

Jan 1, 2019 Osteoadherin (also termed osteomodulin) is encoded by the Omd gene and is a keratan sulfate proteoglycan of the class II subfamily of SLRPs. Mar 30, 2020 localization indicating that this reactivity was due to another KS-proteoglycan, possibly osteoadherin. (osteomodulin) which has known roles in Human Osteoadherin/Osteomodulin quantitates human Osteoadherin/ Osteomodulin in serum, plasma, supernatant. The assay will exclusively recognize both Glycoproteins, such as alkaline phosphatase, osteonectin, RGD-containing proteins (osteoadherin, thrombospondin, fibronectin, vitronectin, osteopontin, bone Apr 18, 2018 Bone matrix proteins: isolation and characterization of a novel cell-binding keratan sulfate proteoglycan (Osteoadherin) from bovine bone. J. Cell Jan 28, 2020 The tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of heparin-binding The regulation of osteoadherin by neurotrophins in both osteoblasts and dental pulp cells suggests that a complex signaling network occurs during the NP_005005.1 osteomodulin 229 OMD_HUMAN Osteomodulin precursor ( Osteoadherin) (OSAD) (Keratan sulfate. Q99983 proteoglycan osteomodulin) ( KSPG Osteoadherin is highly expressed in mineralized tissues, including bone and dentin; however, it's precise roles remain unknown.

Osteoadherin is highly expressed in mineralized tissues, including bone and dentin; however, it's precise roles remain unknown. The present study determined the Omd expression levels and investigated the effects of over‑ and under‑expression of osteoadherin in osteoblastic cells. Our Osteoadherin/OSAD/OMD Antibodies can be used in a variety of model species: Human, Mouse. Use the list below to choose the Osteoadherin/OSAD/OMD Antibody which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and related products. Country/Region selector.
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Read "Osteoadherin is Upregulated by Mature Osteoblasts and Enhances Their InVitro Differentiation and Mineralization, Calcified Tissue International" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Leucine‐rich repeats (LRRs) with 20–30 amino acids in unit length are present in many proteins from prokaryotes to eukaryotes. The LRR‐containing proteins include a family of nine small proteoglycans, forming three distinct subfamilies: class I contains biglycan/PG‐I and decorin/PG‐II; class II: lumican, fibromodulin, PRELP, keratocan, and osteoadherin; and class III: epiphycan/PG The small leucine-rich repeat proteins (SLRPs), fibromodulin and osteoadherin, have N-terminal extensions with a variable number of O-sulfated tyrosine residues. This modification combined with a number of aspartic and glutamic acid residues results in a highly negatively charged domain of less than 30 amino acids.

Use the list below to choose the Osteoadherin/OSAD/OMD Antibody which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and related products. Country/Region selector. Utility Header Menu Right.
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2017-02-28 Osteomodulin (also called osteoadherin or osteoadherin proteoglycan) is a protein that in humans is encoded by the OMD gene. References Further reading. This page was last edited on 12 October 2020, at 04:35 (UTC).

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See more Osteoadherin/OSAD/OMD products: Catalog# EK2017: Storage & Handling: Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.) Description: Sandwich High Sensitivity ELISA kit for Quantitative Detection of human Osteoadherin. 96wells/kit, with removable strips. Cite This Product Bovine osteoadherin contains leucine-rich repeats (LRRs) and is also rich in aspartic acid and glutamic acid. It had an apparent molecular mass of 85 kD under reducing conditions by SDS-PAGE.